A na-eji obere abụba dị mkpụmkpụ, gụnyere butyrate na ụdị ya, eme ihe dị ka ihe mgbakwunye nri iji gbanwee ma ọ bụ belata mmetụta ọjọọ nke ihe ndị sitere na osisi na nri aquaculture, ma nwee ọtụtụ mmetụta physiological na-akwalite ahụike na anụmanụ na anụ ụlọ. A na-enyocha Tributyrin, nke bụ butyric acid sitere, dị ka ihe mgbakwunye na nri anụmanụ a na-akọ ugbo, yana nsonaazụ dị mma na ọtụtụ ụdị. Na azụ na crustaceans, itinye tributyrin nri dị ọhụrụ ma a naghị amụcha ya nke ọma mana nsonaazụ na-egosi na ọ nwere ike ịba uru nke ukwuu maka anụmanụ mmiri. Nke a dị mkpa karịsịa maka ụdị anụ na-eri anụ, ndị a chọrọ ka e mee ka nri ha ka mma iji belata ọdịnaya azụ azụ iji mee ka nchekwa gburugburu ebe obibi na akụ na ụba nke ngalaba ahụ dịkwuo mma. Ọrụ a na-akọwa tributyrin ma na-egosi isi ihe si na ojiji ya dị ka isi iyi nri nke butyric acid na nri maka ụdị mmiri. Isi ihe a na-elekwasị anya bụ ụdị aquaculture na otu tributyrin, dị ka ihe mgbakwunye nri, nwere ike isi tinye aka na imeziwanye aquafeeds sitere na osisi.
2. Glyceryl butyrate
Asịd Butyric nwere isi na-adịghị mma ma dịkwa mfe ịgbaze, ọ na-esikwa ike iru azụ eriri afọ iji rụọ ọrụ mgbe anụmanụ riri ya, yabụ enweghị ike iji ya ozugbo na mmepụta. Glyceryl butyrate bụ ngwaahịa abụba nke butyric acid na glycerin. Asịd Butyric na glycerin na-ejikọta site na njikọ covalent. Ha kwụsiri ike site na pH1-7 ruo 230 ℃. Mgbe anụmanụ riri ya, glyceryl butyrate anaghị ere ere n'afọ, kama ọ na-agbaze ghọọ butyric acid na glycerin n'ime eriri afọ n'okpuru ọrụ nke lipase pancreatic, na-ewepụta butyric acid nwayọ nwayọ. Glyceryl butyrate, dị ka ihe mgbakwunye nri, dị mfe iji, dị nchebe, anaghị egbu egbu, ma nwee ụtọ pụrụ iche. Ọ bụghị naanị na ọ na-edozi nsogbu na butyric acid siri ike ịgbakwunye dị ka mmiri mmiri ma na-esi isi ọjọọ, kamakwa ọ na-eme ka nsogbu ahụ ka mma na butyric acid siri ike iru eriri afọ mgbe ejiri ya ozugbo. A na-ewere ya dị ka otu n'ime ihe ndị kacha mma sitere na butyric acid na ngwaahịa antihistamine.
2.1 Glyceryl Tributyrate na Glyceryl Monobutyrate
Tributyrinnwere molekul butyric acid atọ na molekul glycerol otu. Tributyrin ji nwayọ wepụta butyric acid n'ime eriri afọ site na pancreatic lipase, akụkụ ya na-apụta n'ihu eriri afọ, akụkụ ya nwekwara ike iru azụ eriri afọ iji rụọ ọrụ; A na-emepụta monobutyric acid glyceride site na otu molekul butyric acid nke na-ejikọ na ebe mbụ nke glycerol (Sn-1 site), nke nwere ihe onwunwe hydrophilic na lipophilic. Ọ nwere ike iru njedebe azụ nke eriri afọ site na mmiri nri. A na-ewepụta ụfọdụ butyric acid site na pancreatic lipase, ụfọdụ na-abanyekwa ozugbo site na mkpụrụ ndụ epithelial eriri afọ. A na-agbaze ya ka ọ bụrụ butyric acid na glycerol na mkpụrụ ndụ mucosal eriri afọ, na-akwalite uto nke eriri afọ villi. Glyceryl butyrate nwere polarity molecular na nonpolarity, nke nwere ike ịbanye n'ime akpụkpọ ahụ hydrophilic ma ọ bụ lipophilic cell membrane nke nje bacteria bụ isi na-akpata ọrịa, wakpo mkpụrụ ndụ nje bacteria, bibie usoro sel, ma gbuo nje bacteria na-emerụ ahụ. Mkpụrụ ọgwụ monobutyric acid glyceride nwere mmetụta siri ike nke nje bacteria gram-positive na nje bacteria gram-negative, ma nwee mmetụta ka mma nke nje bacteria.
2.2 Itinye glyceryl butyrate n'ime ngwaahịa mmiri
Glyceryl butyrate, dị ka ihe sitere na butyric acid, nwere ike iwepụta butyric acid nke ọma n'okpuru ọrụ nke lipase pancreas nke eriri afọ, ọ dịghịkwa isi, kwụsiri ike, dị nchebe ma nwee ihe fọdụrụ. Ọ bụ otu n'ime ụzọ kachasị mma maka ọgwụ nje ma a na-ejikarị ya eme ihe n'ugbo mmiri. Zhai Qiuling na ndị otu ya gosiri na mgbe etinyere 100-150 mg/kg tributylglycerol ester na nri ahụ, ọnụego mmụba ibu, ọnụego uto kpọmkwem, ọrụ nke enzymes nri dị iche iche na ịdị elu nke eriri afọ villi tupu na mgbe etinyere 100 mg/kg tributylglycerol ester nwere ike ịbawanye nke ukwuu; Tang Qifeng na ndị nchọpụta ndị ọzọ chọpụtara na itinye 1.5g/kg tributylglycerol ester na nri ahụ nwere ike ime ka arụmọrụ uto nke Penaeus vannamei ka mma nke ukwuu, ma belata ọnụọgụ nke nje virus na-akpata ọrịa n'ime eriri afọ nke ukwuu; Jiang Yingying et al. achọpụtara na itinye 1g/kg nke tributyl glyceride na nri ahụ nwere ike ime ka ọnụego ibu nke Allogenetic crucian carp dịkwuo elu nke ukwuu, belata ọnụọgụ nri, ma mee ka ọrụ nke superoxide dismutase (SOD) dịkwuo elu na hepatopancreas; Ụfọdụ ọmụmụ gosiri na mgbakwunye nke 1000 mg/kgtributyl glyceridenri nwere ike ime ka ọrụ Jian carp nke superoxide dismutase (SOD) nke eriri afọ dịkwuo elu nke ukwuu.
Oge ozi: Jenụwarị-05-2023
