Ruo ọtụtụ iri afọ, ejirila butyric acid mee ihe n'ụlọ ọrụ nri iji melite ahụike afọ na arụmọrụ anụmanụ. E webatara ọtụtụ ọgbọ ọhụrụ iji melite njikwa ngwaahịa na arụmọrụ ya kemgbe e mere nnwale mbụ na afọ 80.

Ruo ọtụtụ iri afọ, ejirila butyric acid mee ihe n'ụlọ ọrụ nri iji melite ahụike afọ na arụmọrụ anụmanụ. E webatara ọtụtụ ọgbọ ọhụrụ iji melite njikwa ngwaahịa na arụmọrụ ya kemgbe e mere nnwale mbụ na afọ 1980.

1 Mmepe nke butyric acid dị ka ihe mgbakwunye nri

Achịcha Butyric nke afọ 1980 ka e ji mee ka uto rumen ka mma.
Nnu nke butyrin acid nke afọ 1990 ji mee ka ọrụ anụmanụ ka mma
Nnu ndị a kpụchara akpụkọ nke afọ 2000 mepụtara: eriri afọ ka mma na obere isi
2010s> E webatara acid butyric ọhụrụ esterified ma dị irè karịa

Taa, ahịa ahụ nwere butyric acid echekwara nke ọma. Ndị na-emepụta nri na-eji ihe mgbakwunye ndị a enweghị nsogbu na nsogbu isi, mmetụta nke ihe mgbakwunye na-enwe na ahụike na arụmọrụ afọ ka mma. Nsogbu dị na ngwaahịa mkpuchi nkịtị bụ obere mkpokọta butyric acid. Nnu mkpuchi na-enwekarị 25-30% butyric acid, nke dị obere nke ukwuu.

Mmepe kachasị ọhụrụ na ihe mgbakwunye nri dabere na butyric acid bụ mmepe nke ProPhorce™ SR: glycerol esters nke butyric acid. Enwere ike ịchọta triglycerides ndị a nke butyric acid n'ụzọ ebumpụta ụwa na mmiri ara ehi na mmanụ aṅụ. Ha bụ isi iyi kachasị mma nke butyric acid echekwara yana mkpokọta butyric acid ruo 85%. Glycerol nwere ohere inwe molekul butyric acid atọ ejikọtara na ya site na ihe a na-akpọ 'ester bonds'. Njikọ ndị a dị ike dị na triglycerides niile ma enwere ike ịgbaji ha naanị site na enzymes kpọmkwem (lipase). N'ime ihe ubi na afọ, tributyrin na-anọgide na-adịgide adịgide, na n'ime eriri afọ ebe pancreatic lipase dị mfe ịnweta, a na-ewepụta butyric acid.

Usoro esterifying butyric acid egosila na ọ bụ ụzọ kachasị dị irè isi mepụta butyric acid na-enweghị isi nke a na-ewepụta ebe ịchọrọ ya: n'afọ. E depụtara ọdịiche dị na nnu a kpuchiri ekpuchi na fig. 2.

N'oge asọmpi ESPN nke iri abụọ na Prague, e gosipụtara ọmụmụ ihe atụnyere mmetụta nke ihe mgbakwunye butyric acid abụọ dị iche iche na broilers. E mere nnwale ahụ na ebe nyocha ADAS dị na UK na 2014. Ha tụnyere nnu sodium a kpụchara akpụ (nke nwere mkpuchi 68%) na ProPhorce™ SR 130 (55% butyric acid). E kewara ụmụ ọkụkọ nwoke 720 Coss308 n'ime otu atọ, ya na mkpịsị iri na abụọ nke nnụnụ 20 kwa otu. Iji mee ka ọnọdụ azụmahịa dị ka o kwere mee, etinyere ihe ruru unyi mgbe nyochachara ọrịa nje, nje bacteria na nje virus.

Ọrụ Tributyrin

1. Na-edozi obere eriri afọ anụmanụ ma na-egbochi nje bacteria na-emerụ ahụ.

2. Na-eme ka mmịpụta na ojiji nke ihe ndị na-edozi ahụ ka mma.

3. Nwere ike ibelata afọ ọsịsa na nrụgide nke ụmụ anụmanụ na-eto eto.

4. Na-eme ka ọnụọgụ ndụ na mmụba ibu kwa ụbọchị nke anụmanụ ndị na-eto eto dịkwuo elu.